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Troponin bound to heparin causes lower calculated troponin plasma focus when compared to serum.[76] Other resources of interference that will affect the assay detection system and induce Phony-negative troponin values involve ascorbic acid in immunoenzymometric assays utilizing alkaline phosphatase, biotin in assays employing a biotinylated antibody, streptokinase from the presence of streptavidin, and higher titers of antibodies to ruthenium or streptavidin in cTnT assays.

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